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Merck
CN

Y0000054

前列地尔

European Pharmacopoeia (EP) Reference Standard

别名:

前列腺素 E1, (11α,13E,15S)-11,15-二羟基-9-氧代前列-13-烯-1-酸, PGE1, 前列地尔

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关于此项目

经验公式(希尔记法):
C20H34O5
化学文摘社编号:
分子量:
354.48
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
212-017-2
Beilstein/REAXYS Number:
5294062
MDL number:
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InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

SMILES string

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

grade

pharmaceutical primary standard

API family

alprostadil

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

Gene Information

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Alprostadil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Takashi Onoe et al.
Transplantation, 95(12), 1521-1527 (2013-04-20)
Small-for-size syndrome remains the greatest limiting factor of expanding segmental liver transplantation from living donors. Portal hyperperfusion is considered to substantially contribute to small-for-size syndrome. We investigated the impact of continuous portal infusion of prostaglandin E1 (PGE1) on small-for-size grafts
J G Ray
Transplantation, 66(4), 476-483 (1998-09-12)
To assess whether prostaglandin E1 analogs have a role in either reducing renal allograft rejection or improving renal function among both transplant and nontransplant patients. Studies were identified through Ovid MEDLINE between 1981 and December 1997 using multiple MeSH headings
Michael Berner et al.
The journal of sexual medicine, 9(12), 3089-3107 (2012-10-24)
As yet, a summary of research evidence concerning the efficacy of psychological treatment in male sexual dysfunction is lacking. Our systematic review gives an overview of the efficacy of psychosocial interventions in all male sexual dysfunctions. Main outcome measures included
A Creutzig et al.
VASA. Zeitschrift fur Gefasskrankheiten, 33(3), 137-144 (2004-10-06)
The relevance of Prostaglandin El (PGE,) in the treatment of peripheral arterial occlusive disease stage III and IV was to be evaluated for the first time by a meta-analysis. Altogether, 643 patients were analyzed from seven randomized, controlled PGE1 studies
K Schrör et al.
VASA. Zeitschrift fur Gefasskrankheiten, 33(3), 119-124 (2004-10-06)
The mechanisms of anti-ischemic effects of PGE1 in patients with peripheral arterial occlusive disease (PAD) are probably complex and clearly not limited to a direct vasodilator action. In addition to the known effects on blood flow, viscosity, fibrinolysis and platelet

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