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Merck
CN

Y0000144

甲苯咪唑

European Pharmacopoeia (EP) Reference Standard

别名:

甲苯咪唑, 5-苯甲酰-2-苯并咪唑胺甲酸甲酯, 甲基N-(5-苯甲酰基-1H-苯并咪唑-2-基)氨基甲酸酯

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关于此项目

经验公式(希尔记法):
C16H13N3O3
化学文摘社编号:
分子量:
295.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
759809
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产品名称

甲苯咪唑, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

mebendazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Mebendazole for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mebendazole and related anthelmintics.
H Van den Bossche et al.
Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)
Olga Staudacher et al.
Tropical medicine & international health : TM & IH, 19(7), 812-824 (2014-04-23)
Preventive chemotherapy of schoolchildren against soil-transmitted helminths (STHs) is widely implemented in Rwanda. However, data on its actual efficacy are lacking. We assessed prevalence, associated factors and manifestation of STH infection among schoolchildren in southern highland Rwanda as well as
T Inaoka et al.
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 62(1), 54-67 (1987-01-01)
The effects of the mebendazole, albendazole and ivermectin on secondary multilocular echinococcosis in Chinese hamsters infected with intraperitoneal inoculation of protoscolices and in rats infected with transportal inoculation of protoscolices were investigated. A reduction in weight of the hydatids greater
R Cañete et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 103(5), 437-442 (2009-02-07)
Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis. However, it has been demonstrated that its spectrum of activity is broad and goes beyond those infections. Several studies provide evidence
[Nonspecific abdominal symptoms. What is going on in the intestine?].
Peter Stiefelhagen
MMW Fortschritte der Medizin, 156(21-22), 44-44 (2015-01-23)

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