Y0000358
氯法齐明
European Pharmacopoeia (EP) Reference Standard
别名:
氯法齐明
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经验公式（希尔记法）:
C27H22Cl2N4
化学文摘社编号:
分子量:
473.40
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
pharmaceutical primary standard
API类
clofazimine
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CC(C)\N=C1/C=C2N(c3ccc(Cl)cc3)c4ccccc4N=C2C=C1Nc5ccc(Cl)cc5
InChI
1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3/b30-24+
InChI key
WDQPAMHFFCXSNU-BGABXYSRSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Clofazimine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
The pharmacology, metabolism, and chemistry of clofazimine.
R O'Connor et al.
Drug metabolism reviews, 27(4), 591-614 (1995-01-01)
Lamprene (clofazimine) in leprosy. Basic information.
S J Yawalkar et al.
Leprosy review, 50(2), 135-144 (1979-06-01)
Clofazimine--a review.
B Kumar
Indian journal of leprosy, 63(1), 78-92 (1991-01-01)
Anthony V Pais et al.
Leprosy review, 75(2), 171-176 (2004-07-31)
We report a case with abdominal complications of clofazimine treatment which included blackish discolouration of the lymph nodes, omentum and peritoneum. A 44-year-old female with lepromatous leprosy and a history of adverse reaction to clofazimine 2 years previously, presented with
E Freerksen et al.
Arzneimittel-Forschung, 42(10), 1243-1245 (1992-10-01)
The usefulness of clofazimine (CLO, CAS 2030-63-9) in the treatment of mycobacterial infections with special emphasis on treatment of leprosy is critically discussed. Skin discolouration which decreases compliance, placenta passage, excretion in mother's milk which endanger the embryo or baby
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