产品名称
丝裂霉素, European Pharmacopoeia (EP) Reference Standard
SMILES string
N21[C@]([C@H]4N[C@H]4C2)([C@@H](C3=C1C(=O)C(=C(C3=O)N)C)COC(=O)N)OC
InChI key
NWIBSHFKIJFRCO-WUDYKRTCSA-N
InChI
1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
grade
pharmaceutical primary standard
API family
mitomycin
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Mitomycin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Carc. 2
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
P Numthavaj et al.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 38(3), 198-207 (2013-04-05)
Mitomycin C has recently been used to prevent nasal synechiae and sinus ostium stenosis after endoscopic sinus surgery. To compare nasal synechiae rate between topical Mitomycin C and saline or no treatment. Systematic review and meta-analysis. MEDLINE, SCOPUS, and Cochrane
Olaf Sørensen et al.
Journal of surgical oncology, 109(6), 521-526 (2013-12-19)
Patients with peritoneal surface malignancies are treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, commonly using mitomycin C (MMC). The purpose of this study was to investigate impact of hyperthermia on pharmacokinetics of intraperitoneal MMC. In 14 athymic nude male
Multimodal keloid therapy with excision, application of mitomycin C, and radiotherapy.
Matthew Willett et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 40(4), 480-482 (2014-01-21)
Jianfeng Xiang et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(4), 3517-3524 (2013-12-07)
Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies in the world whose chemoprevention became increasingly important in HCC treatment. Although the anticancer effects of asparagus constituents have been investigated in several cancers, its effects on hepatocellular carcinoma have
Ingeborg B Fraunholz et al.
Diseases of the colon and rectum, 57(4), 423-431 (2014-03-13)
Despite the increasing evidence for chemoradiotherapy as standard treatment for anal cancer in patients with HIV infection, there is still some uncertainty regarding increased toxicity and adverse effects on the immune status. We report the clinical outcome of 5-fluorouracil/mitomycin C-based
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