agency
EP
InChI
1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
SMILES string
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
InChI key
ZAKOWWREFLAJOT-CEFNRUSXSA-N
biological source
synthetic
grade
pharmaceutical primary standard
API family
tocopherol
form
solid
manufacturer/tradename
EDQM
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
density
0.96 g/mL at 20 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
All-rac-alpha-tocopheryl acetate, the ester of all-rac-alpha-tocopherol, is a commercial form of vitamin E. It is responsible for the protection of phenol groups of the parent tocopherol against oxidation.
All-rac-alpha-tocopheryl acetate, the ester of all-rac-alpha-tocopherol, is a commercial form of vitamin E. It is responsible for the protection of phenol groups of the parent tocopherol against oxidation.
Application
All-rac-alpha-tocopheryl acetate for peak identification may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
No data available
flash_point_c
No data available
all-rac-?-Tocopheryl acetate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 129(7), 3802-3804 (2011)
All-rac-alpha-tocopherol acetate is a better vitamin E source than all-rac-alpha-tocopherol succinate for broilers
Jensen S, et al.
The Journal of Nutrition, 129(7), 1355-1360 (1999)
Succinic Acids?Advances in Research and Application: 2013 Edition: ScholarlyBrief
Acton QA
Succinic Acids?Advances in Research and Application (2013)
Po-Hsien Huang et al.
Science signaling, 6(267), ra19-ra19 (2013-03-21)
Vitamin E is a fat-soluble vitamin with antioxidant properties. Tocopherols are the predominant form of vitamin E found in the diet and in supplements and have garnered interest for their potential cancer therapeutic and preventive effects, such as the dephosphorylation
Katharina M Espe et al.
Clinical journal of the American Society of Nephrology : CJASN, 8(3), 452-458 (2013-01-22)
Trials with the antioxidant vitamin E have failed to show benefit in the general population. Considering the different causes of death in ESRD, this study investigated the association between plasma concentrations of α-tocopherol and specific clinical outcomes in diabetic hemodialysis
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