Merck
CN

Y0000487

来氟米特杂质A

European Pharmacopoeia (EP) Reference Standard

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别名:
4-(三氟甲基)苯胺, α,α,α-三氟对甲苯胺, 4-氨基三氟甲苯
线性分子式:
CF3C6H4NH2
CAS号:
分子量:
161.12
Beilstein:
1564853
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API family

leflunomide

manufacturer/tradename

EDQM

折射率

n20/D 1.483 (lit.)

bp

83 °C/12 mmHg (lit.)

密度

1.283 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

SMILES string

Nc1ccc(cc1)C(F)(F)F

InChI

1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2

InChI key

ODGIMMLDVSWADK-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Leflunomide impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


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B A Maguire et al.
Biochimica et biophysica acta, 1353(2), 137-147 (1997-08-07)
The rpmB,G operon of Escherichia coli codes for proteins L28 and L33 of the larger (50S) ribosomal subunit. Strains with mutations in this operon can help define the roles of these proteins in ribosome synthesis and function. One such strain
B A Maguire et al.
Journal of bacteriology, 179(8), 2486-2493 (1997-04-01)
The rpmBG operon of Escherichia coli codes for ribosomal proteins L28 and L33. Two strains with mutations in the operon are AM81, whose ribosomes lack protein L28, and AM90, whose ribosomes are without protein L33. Neither strain showed major defects
Guiping Ouyang et al.
Molecules (Basel, Switzerland), 10(10), 1351-1357 (2007-11-17)
A facile synthesis of 3-methylthio-3-arylamino-2-cyanoacrylates from 3,3-dimethylthioacrylate and aromatic amines or amino pyridines has been achieved in moderate to high yields (64.0% ~ 93.5%) in 30 minutes at 50 degrees C under microwave irradiation. This method is very simple and
T Kunisawa
Journal of theoretical biology, 213(1), 9-19 (2001-11-16)
A simple method is presented for reconstructing phylogenetic trees on the basis of gene transposition. It is shown that differences in gene arrangements among genomes could allow us to determine whether a gene transposition event has occurred before or after
H Klein
Biochemistry and cell biology = Biochimie et biologie cellulaire, 75(2), 177-182 (1997-01-01)
A cDNA coding for the hamster S24 ribosomal protein was used to isolate homologous genes from a Syrian hamster fibroblast genomic library. Southern analysis, using S24 ribosomal protein cDNA and two probes derived from the 5' and 3' ends, suggests

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