Y0000538
Dexamethasone isonicotinate
European Pharmacopoeia (EP) Reference Standard
别名:
Dexamethasone 21-isonicotinate
等级
pharmaceutical primary standard
API类
dexamethasone
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
F[C@@]21[C@H]([C@H]4[C@@]([C@@]([C@@H](C4)C)(O)C(=O)COC(=O)c5ccncc5)(C[C@@H]2O)C)CCC3=CC(=O)C=C[C@@]31C
InChI
1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1
InChI key
BQTXJHAJMDGOFI-NJLPOHDGSA-N
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Dexamethasone isonicotinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
法规信息
涉药品监管产品
此项目有
Laurent L Couëtil et al.
Journal of veterinary internal medicine, 20(2), 399-406 (2006-04-06)
Glucocorticoid (GC) therapy is recognized to be effective for the treatment of recurrent airway obstruction (RAO) in horses. Anti-inflammatory properties of GC are thought to be mediated by suppression of inflammatory gene expression via inhibition of transcription factors such as
G Hochhaus et al.
Journal of pharmaceutical and biomedical analysis, 9(9), 761-767 (1991-01-01)
A combined LC/RIA procedure is described for the selective determination of dexamethasone (DEX) and its prodrug dexamethasone-21-isonicotinate (DIN) in plasma. The low affinity of the employed dexamethasone antiserum for DIN (cross-reactivity less than 0.5%) allowed the direct determination of DEX
Ersilia Pappalardo et al.
Veterinary dermatology, 13(6), 331-336 (2002-12-05)
A 7-year-old-female goat was referred with a 3-month history of chronic dermatitis, which partially responded to combined corticosteroid and antibiotic therapy. At dermatological examination diffuse alopecia, pustules and crusts were observed on the head, neck, dorsum and perianal area. Dermatophyte
[Modern aerosols in the treatment of obstructive respiratory tract diseases. 3. Inhalable corticoids].
D Heide
Zeitschrift fur arztliche Fortbildung, 78(2), 49-51 (1984-01-01)
[Vorenicol and Bisolvon: advice].
J F Nouws
Tijdschrift voor diergeneeskunde, 106(22), 1166-1168 (1981-11-15)
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