SMILES string
[Cl-].[Cl-].N(CCCCCCNCCc2ccccc2)CCc1cc(c(cc1)O)O.[H+].[H+]
InChI
1S/C22H32N2O2.2ClH/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19;;/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2;2*1H
InChI key
VPDULUNRSQWWJB-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
dopexamine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Dopexamine dihydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
Rupert M Pearse et al.
Critical care medicine, 36(4), 1323-1329 (2008-04-02)
To establish whether perioperative low-dose dopexamine infusion (< or = 1 microg/kg/min) is associated with a reduction in mortality and duration of hospital stay following major surgery. Medline, EMBASE, CINAHL, Cochrane Library, Google Scholar, and reference lists. Two reviewers independently
Jurgen Birnbaum et al.
Critical care (London, England), 10(4), R117-R117 (2006-08-09)
The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats. This prospective, randomized, controlled laboratory study was conducted in
N E El Mokhtari et al.
European journal of medical research, 13(10), 459-463 (2008-11-15)
To examine the effects of a therapy with dopexamine/dopamine in comparison with a regimen of dobutamine/dopamine on the outcome of patients with profound cardiogenic shock. Twenty patients presenting with an acute cardiogenic shock assisted with mechanical ventilation, being refractory to
Reiner Oberbeck
Current medicinal chemistry, 13(17), 1979-1989 (2006-07-18)
The existence of an immune-endocrine interaction has been reported and the modulatory effects of the natural occurring catecholamines epinephrine, norepinephrine and dopamine as well as of pharmaceutically generated catecholamines like dopexamine on a wide variety of immune functions were demonstrated.
Dopexamine and survival: areas of consistency.
R Pearse et al.
Anaesthesia, 64(11), 1258-1258 (2009-10-15)
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