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Merck
CN

Y0000709

Oxitropium bromide

European Pharmacopoeia (EP) Reference Standard

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关于此项目

经验公式(希尔记法):
C19H26BrNO4
化学文摘社编号:
分子量:
412.32
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

pharmaceutical primary standard

API类

oxitropium

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[Br-].[N+]1(C2C3OC3C1CC(C2)OC(=O)C(CO)c4ccccc4)(CC)C

InChI

1S/C19H26NO4.BrH/c1-3-20(2)15-9-13(10-16(20)18-17(15)24-18)23-19(22)14(11-21)12-7-5-4-6-8-12;/h4-8,13-18,21H,3,9-11H2,1-2H3;1H/q+1;/p-1

InChI key

LCELQERNWLBPSY-UHFFFAOYSA-M

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Oxitropium bromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cristoforo Incorvaia et al.
Respiratory medicine, 101(3), 476-480 (2006-08-22)
Inhaled bronchodilators are first line drugs in the treatment of chronic obstructive pulmonary disease (COPD). Tiotropium bromide is a recently introduced long-acting anticholinergic agent able to reduce dyspnoea and COPD exacerbations and to improve pulmonary function and quality of life.
Bruno Sposato et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 45(5), 397-401 (2008-06-24)
The protective effect of inhaled anticholinergic drugs in the methacholine-induced bronchospasm is well-known. The objective of this study was to assess if any possible differences may be found among Ipratropium (IB), Oxitropium (OXI) and Tiotropium (TIO) pre-treatments to obtain the
Kai-Michael Beeh et al.
Respiration; international review of thoracic diseases, 69(4), 372-379 (2002-08-10)
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality in the world. In the majority of cases, the disease is the result of years of cigarette smoking. Contributing factors leading to bronchial obstruction in
Y Nakano et al.
The Journal of allergy and clinical immunology, 106(3), 472-478 (2000-09-13)
The efficacy of combination therapy adding multiple doses of anticholinergics to beta(2)-agonists to improve outcome has not been established in adults with acute severe asthma. This study was undertaken to compare the outcome of adults with acute severe asthma treated
Takanobu Shioya et al.
Arzneimittel-Forschung, 58(1), 24-28 (2008-03-29)
The present study was undertaken to evaluate the long-term effect of procaterol hydrochloride (CAS 62929-91-3, Meptin), a third generation beta2-receptor agonist on lung function, exercise capacity, health-related quality of life (HRQOL) and activities of daily living (ALDs) in patients with

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