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Y0001149

盐酸小檗碱

Name: 盐酸小檗碱
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

小檗碱 CRM 氯化物形式, 黄连素

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关于此项目

经验公式（希尔记法）:

C₂₀H₁₈ClNO₄

化学文摘社编号:

633-65-8

分子量:

371.81

PubChem Substance ID:

329830786

UNSPSC Code:

41116107

NACRES:

NA.24

MDL number:

MFCD00011939

Colour Index Number:

75160

Beilstein/REAXYS Number:

3836585

eCl@ss:

25140904

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属性

grade

pharmaceutical primary standard

API family

berberine

manufacturer/tradename

EDQM

application(s)

pharmaceutical
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

肥大细胞中肝素的荧光染色

Biochem/physiol Actions

一种抗生素特性较弱的生物碱。MDR外排泵的底物。小檗碱的抗微生物活性可通过MDR抑制剂5'-甲氧基氢化物（5'-MHC）加强。小檗碱可上调肝癌细胞中Pgp的表达。用小檗碱进行治疗可能会减少化学治疗药物的积累。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

怎么回事？

WGK 2

闪点 (F)

Not applicable

闪点 (°C)