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Merck
CN

Y0001220

卡托普利杂质C

European Pharmacopoeia (EP) Reference Standard

别名:

(2RS)-2-Methyl-3-sulphanylpropanoic acid, 3-Mercaptoisobutyric acid

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关于此项目

经验公式(希尔记法):
C4H8O2S
化学文摘社编号:
分子量:
120.17
UNSPSC Code:
41116107
NACRES:
NA.24
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产品名称

卡托普利杂质C, European Pharmacopoeia (EP) Reference Standard

SMILES string

[Na+].SCC(C)C(=O)[O-]

InChI

1S/C4H8O2S.Na/c1-3(2-7)4(5)6;/h3,7H,2H2,1H3,(H,5,6);/q;+1/p-1

InChI key

FOTPRJUNQGWLCM-UHFFFAOYSA-M

grade

pharmaceutical primary standard

API family

captopril

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

Application

Captopril impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of enantiomeric purity of 3-mercapto-2-methylpropionic acid.
D Wang-Iverson et al.
Journal of chromatography, 408, 365-371 (1987-11-06)
T C Tallant et al.
Journal of bacteriology, 179(22), 6902-6911 (1997-11-26)
During growth on acetate, Methanosarcina barkeri expresses catabolic enzymes for other methanogenic substrates such as monomethylamine. The range of substrates used by cells grown on acetate was further explored, and it was found that cells grown on acetate also converted
Erinn C Howard et al.
Science (New York, N.Y.), 314(5799), 649-652 (2006-10-28)
Flux of dimethylsulfide (DMS) from ocean surface waters is the predominant natural source of sulfur to the atmosphere and influences climate by aerosol formation. Marine bacterioplankton regulate sulfur flux by converting the precursor dimethylsulfoniopropionate (DMSP) either to DMS or to
M R Smith et al.
Bioorganic & medicinal chemistry, 2(7), 589-593 (1994-07-01)
A bacterium (strain photoB) photoassimilated 3-mercapto-2-methylpropionate as sole source of sulphur with methacrylate accumulating in the medium. This was thought to be the product of a sulphur-lyase type enzyme attacking the 3-mercapto-2-methylpropionate. Detailed examination of the biochemistry of the utilization
H G Brittain et al.
Pharmaceutical research, 7(10), 1082-1085 (1990-10-01)
The ultraviolet and circular dichroism spectra of authentic captopril have been obtained, since the reported literature data are inconsistent with those obtained on highly purified material. The UV absorption spectrum consists of a single band maximum at 200 nm, while

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