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文件

Y0001256

2-羟基吡啶

Name: 2-羟基吡啶
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

2(1H)-吡啶酮, 2-吡啶醇

经验公式（希尔记法）:

C₅H₅NO

CAS号:

142-08-5

分子量:

95.10

Beilstein:

105757

MDL编号:

MFCD00006268

PubChem化学物质编号:

329831326

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

levetiracetam

制造商/商品名称

EDQM

bp

280-281 °C (lit.)

mp

105-107 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

Oc1ccccn1

InChI

1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)

InChI key

UBQKCCHYAOITMY-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Levetiracetam impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Danger

危险声明

H301

预防措施声明

P301 + P330 + P331 + P310

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

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Efficient synthesis of biazoles by aerobic oxidative homocoupling of azoles catalyzed by a copper(I)/2-pyridonate catalytic system.

Mingwen Zhu et al.

Chemical communications (Cambridge, England), 47(48), 12876-12878 (2011-11-15)

A highly efficient and convenient CuCl/2-pyridonate catalytic system for oxidative homocoupling of azoles affording a biazole product has been developed. With this system, a variety of biazoles have been effectively synthesized in good to excellent yields in the presence of

Design, synthesis, and binding mode prediction of 2-pyridone-based selective CB2 receptor agonists.

Ken-ichi Kusakabe et al.

Bioorganic & medicinal chemistry, 21(7), 2045-2055 (2013-02-12)

Selective CB2 agonists have the potential for treating pain without central CB1-mediated adverse effects. Screening efforts identified 1,2-dihydro-3-isoquinolone 1; however, this compound has the drawbacks of being difficult to synthesize with two asymmetric carbons on an isoquinolone scaffold and of

Enantioselectivity in visible light-induced, singlet oxygen [2+4] cycloaddition reactions (type II photooxygenations) of 2-pyridones.

Christian Wiegand et al.

Chemical communications (Cambridge, England), 48(82), 10195-10197 (2012-09-11)

3-Substituted 2-pyridones were enantioselectively (68-90% ee) converted into the respective 3-hydroxypyridine-2,6-diones by a sequence consisting of a template-mediated type II photooxygenation and an acid-catalysed rearrangement.

Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: templation and inhibition involve oligomers with different structure.

Istvan Horvath et al.

Archives of biochemistry and biophysics, 532(2), 84-90 (2013-02-13)

In a recent study we discovered that a ring-fused 2-pyridone compound triggered fibrillization of a key protein in Parkinson's disease, α-synuclein. To reveal how variations in compound structure affect protein aggregation, we now prepared a number of strategic analogs and

Electron-induced phase transition in hydrogen-bonded solid-state 2-pyridone.

Henryk T Flakus et al.

The journal of physical chemistry. A, 115(6), 1027-1039 (2011-01-21)

This paper presents the results of experimental studies of hydrogen-bonded 2-pyridone crystal IR spectra. Spectral studies have demonstrated the existence of two anhydrous solid-state phases of each compound, namely the α and the β phases. Hydrogen bonds in the high-temperature

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