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Y0001290

和厚朴酚

Name: 和厚朴酚
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

5,3′-Diallyl-2,4′-dihydroxybiphenyl, NSC 293100

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关于此项目

经验公式（希尔记法）:

C₁₈H₁₈O₂

化学文摘社编号:

35354-74-6

分子量:

266.33

NACRES:

NA.24

PubChem Substance ID:

329831346

UNSPSC Code:

41116107

MDL number:

MFCD00016674

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属性

grade

pharmaceutical primary standard

API family

honokiol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

Oc1ccc(cc1CC=C)-c2cc(CC=C)ccc2O

InChI

1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

InChI key

FVYXIJYOAGAUQK-UHFFFAOYSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Honokiol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

和厚朴酚是来自木兰提取物的天然联苯新木脂素。它具有抗血管生成、抗肿瘤和抗焦虑的作用。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS05,GHS09

signalword

Danger

hcodes

H318,H411

pcodes

P273 - P280 - P305 + P351 + P338 - P391 - P501

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition.

Haiquan Wang et al.

Neuropharmacology, 86, 9-21 (2014-06-29)

Recently, increasing evidence has shown that cell cycle activation is a key factor of neuronal death and neurological dysfunction after traumatic brain injury (TBI). This study aims to investigate the effects of Honokiol, a cell cycle inhibitor, on attenuating the

Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes.

Ying Ju Chen et al.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(4), 573-580 (2014-01-01)

Proinflammatory cytokine interleukin-1β (IL-1β) stimulates several mediators of cartilage degradation and plays an important role in the pathogenesis of osteoarthritis (OA). Honokiol, a low molecular weight natural product isolated from the Magnolia officinalis, has been shown to possess anti-inflammatory effect.

Honokiol, a multifunctional tumor cell death inducer.

Wei Tian et al.

Die Pharmazie, 67(10), 811-816 (2012-11-10)

Honokiol is a small-molecule pharmacologically active component which has various medicinal applications. Increasing interest is paid on its multifunctional anti-tumor effects including inducing tumor cell death, anti-angiogenesis, anti-migration and anti-multiple drug resistance. We addressed a brief summary of the anti-tumor

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全球贸易项目编号

货号	GTIN
Y0001290	04061833806951