Y0001352
尼麦角林
European Pharmacopoeia (EP) Reference Standard
别名:
5-溴烟酸 10-甲氧基-1,6-二甲基麦角灵-8-甲酯
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关于此项目
经验公式（希尔记法）:
C24H26BrN3O3
化学文摘社编号:
分子量:
484.39
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
pharmaceutical primary standard
API类
nicergoline
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
[H][C@@]12Cc3cn(C)c4cccc(c34)[C@]1(C[C@@H](COC(=O)c5cncc(Br)c5)CN2C)OC
InChI
1S/C24H26BrN3O3/c1-27-13-17-8-21-24(30-3,19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7,10-11,13,15,21H,8-9,12,14H2,1-3H3/t15-,21-,24+/m1/s1
InChI key
YSEXMKHXIOCEJA-FVFQAYNVSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Nicergoline for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
涉药品监管产品
此项目有
Su-Young Kim et al.
Current eye research, 36(1), 29-33 (2010-12-23)
We wanted to investigate the effect of nicergoline on corneal nerve regeneration in rat corneas after photorefractive keratectomy (PRK). Twenty Sprague-Dawley male rats were divided into two groups, the control group and the group that had been treated with nicergoline
Tetsuya Mizuno et al.
Brain research, 1066(1-2), 78-85 (2005-12-06)
We examined the neuroprotective role of nicergoline in neuron-microglia or neuron-astrocytes co-cultures. Nicergoline, an ergoline derivative, significantly suppressed the neuronal cell death induced by co-culture with activated microglia or astrocytes stimulated with lipopolysaccharide (LPS) and interferon (IFN)-gamma. To elucidate the
V Vitton et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 18(11), 1031-1040 (2006-10-17)
A pontine centre located near the micturition centre controlling external anal sphincter (EAS) motility via noradrenergic neurones has been described in cats. The aim of this study was to determine (i) whether a similar centre controls EAS motility in humans
Mohamed I Walash et al.
Journal of AOAC International, 91(2), 349-359 (2008-05-15)
A rapid, simple, and highly sensitive second-derivative synchronous fluorometric method has been developed for the simultaneous analysis of binary mixtures of cinnarizine (CN) and nicergoline (NIC). The method is based upon measurement of the native fluorescence of these drugs at
Jun-Sub Choi et al.
The ocular surface, 11(1), 16-18 (2013-01-17)
Many factors are involved in the corneal wound healing mechanism, including adhesion, migration, and proliferation of corneal epithelial cells. Abnormal corneal wound healing leads to corneal edema, neovascularization, scar formation, and poor vision. Three agents, 17β-estradiol, nicergoline, and β-glucan, have
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