产品名称
5-硝基-2-糠醛半卡巴腙, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+
SMILES string
NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O
InChI key
IAIWVQXQOWNYOU-FPYGCLRLSA-N
grade
pharmaceutical primary standard
API family
nitrofural
manufacturer/tradename
EDQM
mp
242-244 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Nitrofural for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2
target_organs
male reproductive organs
存储类别
11 - Combustible Solids
wgk
WGK 3
Effect of nitrofurans and NO generators on biofilm formation by Pseudomonas aeruginosa PAO1 and Burkholderia cenocepacia 370.
Zaitseva J, et al.
Research in Microbiology, 160(5), 353-357 (2009)
Teresa del Castillo et al.
ChemMedChem, 9(2), 383-389 (2013-12-18)
Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad hoc synthesis of each cyclodextrin-targeting agent conjugate. We
Nitrofural (nitrofurazone).
IARC monographs on the evaluation of carcinogenic risks to humans, 50, 195-209 (1990-01-01)
[Therapeutically used 5-nitrofural derivatives. Review of literature. 2].
H Kala et al.
Die Pharmazie, 26(4), 193-207 (1971-04-01)
Characterization of the genotoxic properties of nitrofurans: nitrofurazone and furazolidone.
M Kobierska-Szeliga et al.
Acta biochimica Polonica, 41(1), 1-5 (1994-01-01)
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