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文件

Y0001381

氨基葡萄糖

Name: 氨基葡萄糖
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

D- (+)-氨基葡萄糖盐酸盐, 2-氨基-2-脱氧-D-葡萄糖盐酸盐, 壳糖胺盐酸盐

经验公式（希尔记法）:

C₆H₁₃NO₅ · HCl

CAS号:

66-84-2

分子量:

215.63

Beilstein:

4157370

MDL编号:

MFCD00135831

PubChem化学物质编号:

329831394

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

glucosamine

制造商/商品名称

EDQM

mp

190-194 °C (dec.) (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

InChI key

QKPLRMLTKYXDST-NSEZLWDYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Glucosamine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

葡萄糖胺是一种氨基糖，是己糖胺生物合成途径的前体，可导致形成UDP-N-乙酰葡糖胺(UDP-GlcNAc)，然后将其用于制备糖胺聚糖、蛋白多糖和糖脂。 D-（+）-葡萄糖胺抑制念珠菌酵母菌株与细菌菌株唾液链球菌的共聚集。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

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Nanoparticle-based CT imaging technique for longitudinal and quantitative stem cell tracking within the brain: application in neuropsychiatric disorders.

Oshra Betzer et al.

ACS nano, 8(9), 9274-9285 (2014-08-19)

A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution, final fate, and functionality. In this study, we developed a

Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet.

Ji-Sun Hwang et al.

Metabolism: clinical and experimental, 64(3), 368-379 (2014-12-18)

This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD)

Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage.

Khadijeh Jamialahmadi et al.

Environmental toxicology and pharmacology, 38(1), 212-219 (2014-06-25)

Glucosamine (GlcN) is an important precursor in the biochemical synthesis of glycosylated proteins and lipids in human body. It gains importance because of its contribution to human health and its multiple biological and therapeutic effects. In this study, the in

Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation.

Viktor Chesnokov et al.

Cancer cell international, 14, 45-45 (2014-06-17)

We have reported that the glucosamine suppressed the proliferation of the human prostate carcinoma cell line DU145 through inhibition of STAT3 signaling. DU145 cells autonomously express IL-6 and the IL-6/STAT3 signaling is activated. IL-6 receptor subunits are subject to N-glycosylation

Synthesis of a molecularly imprinted polymer to isolate glucosamine from plant extracts by an ionic-non-covalent dual approach.

N Henry et al.

International journal of cosmetic science, 37(2), 196-206 (2014-11-18)

The objective of this study was to synthesize a novel glucosamine-imprinted sorbent based on ionic and non-covalent dual approach to purify glucosamine from chicory root extracts. The synthesis of the molecularly imprinted polymer was optimized in terms of choice of

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