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Merck
CN

Y0001969

依那西普

European Pharmacopoeia (EP) Reference Standard

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关于此项目

化学文摘社编号:
NACRES:
NA.24
UNSPSC Code:
41116107
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产品名称

依那西普, European Pharmacopoeia (EP) Reference Standard

grade

pharmaceutical primary standard

API family

etanercept

manufacturer/tradename

EDQM

application(s)

pharmaceutical

format

neat

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Application

This product is intended for laboratory tests as prescribed in the EP only. Established for use with the monograph(s): 2895.

General description

Etanercept is one of the biologic disease-modifying anti-rheumatic drugs (DMARDs) used to treat rheumatoid arthritis (RA). It acts as a tumor necrosis factor (TNF) antagonist by binding with TNF cytokine or protein, thereby blocking its interaction with cell surface receptors. Thus, etanercept effectively relieves joint inflammation from RA and lowers the disease activity.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Etanercept
European Pharmacopoeia Commission and Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 4979-4983 (2021)
Development of a sensitive enzyme-linked immunosorbent assay for the measurement of biologically active etanercept in patients with ankylosing spondylitis
Wang L, et al.
Journal of Chromatography. B, Biomedical Applications, 1008, 219-224 (2016)
Characterization and application of a unique panel of monoclonal antibodies generated against etanercept
Detrez I, et al.
Journal of Immunology, 196(6), 2879-2884 (2016)
Etanercept concentration in patients with rheumatoid arthritis and its potential influence on treatment decisions: a pilot study
Daien CI, et al.
The Journal of Rheumatology, 39(8), 1533-1538 (2012)
Rheumatiod Arthritis: An Updated Overview of Latest Therapy and Drug Delivery
Kesharwani D, et al.
Journal of pharmacopuncture, 22(4), 210-224 (2019)

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