137279
L-精氨酸
EMPROVE® EXPERT, EP, USP
别名:
(S)-2-氨基-5-胍基戊酸
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线性分子式:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
化学文摘社编号:
分子量:
174.20
UNSPSC Code:
12352209
NACRES:
NA.26
eCl@ss:
32160406
MDL number:
Beilstein/REAXYS Number:
1725413
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
SMILES string
N[C@@H](CCCNC(N)=N)C(O)=O
InChI key
ODKSFYDXXFIFQN-BYPYZUCNSA-N
biological source
non-animal source
agency
EP, USP
product line
EMPROVE® EXPERT
assay
>98.5%
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
mp
222 °C (dec.) (lit.)
solubility
H2O: 100 mg/mL
suitability
suitable for manufacturing use
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)
impurities
endotoxin, residual solvents
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General description
Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.
M-Clarity Program
As part of our Emprove® Program, our raw materials are offered with Emprove® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
M-Clarity Program
As part of our Emprove® Program, our raw materials are offered with Emprove® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.
Application
L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility.
Biochem/physiol Actions
一氧化氮合成酶的底物，可转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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