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安全信息

A8846

Sigma-Aldrich

ProteoMass™ Angiotensin II MALDI-MS Standard

vial of 10 nmol

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别名:
Angiotensin II, mass spec standard
MDL编号:
MFCD00161484
PubChem化学物质编号:
329771018

分子量

monoisotopic mol wt 1,045.5423 Da

质量水平

100

包装

vial of 10 nmol

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc4ccccc4)C(O)=O

InChI

1S/C50H71N13O12/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1

InChI key

CZGUSIXMZVURDU-JZXHSEFVSA-N

Gene Information

human ... AGTR1(185)

相关类别

一般描述

Angiotensin II (Ang II) is part of the renin-angiotensin cascade. It is an octapeptide. Ang II is present in high concentration in cardiac tissue.

应用

ProteoMass™ Angiotensin II MALDI-MS Standard has been used:
  • as peptide calibration standard for MALDI-MS instruments
  • as a reference standard in Liquid chromatography–mass spectrometry (LC-MS/MS) analysis for characterizing RNase and NC1 domain of collagen IV
  • as a standard in testing infrared (IR) laser desorption/ionization (IR-LDI) method

生化/生理作用

Angiotensin II (Ang II) maintains cardiac functionality by coordinating with the angiotensin II receptors. Ang II is recommended for patients with vasodilatory shock.

法律信息

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

相关产品

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

分析证书(COA)

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Molecular weight of different angiotensin II polymers directly determines: Density of endothelial membrane AT1 receptors and coronary vasoconstriction
Torres-Tirado D, et al.
Vascular Pharmacology, 58(5-6), 346-355 (2013)
Continuous flow reduced-pressure infrared laser desorption/ionization mass spectrometry
Iguchi Y, et al.
Rapid Communications in Mass Spectrometry, 31(21), 1845-1850 (2017)
Pyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo
Madu H, et al.
Free Radical Biology & Medicine, 89(5), 83-90 (2015)
Effect of solvent on ionization efficiency in matrix-assisted laser desorption/ionization mass spectrometry of peptides
Hazama H, et al.
Chemical Physics, 419(5), 196-199 (2013)
Ryuji Hiraguchi et al.
International journal of molecular sciences, 15(6), 10821-10834 (2014-06-18)
A continuous flow atmospheric pressure laser desorption/ionization technique using a porous stainless steel probe and a 6-7-µm-band mid-infrared tunable laser was developed. This ion source is capable of direct ionization from a continuous flow with a high temporal stability. The
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One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.

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