P6410
Pancreatic Polypeptide rat
≥95% (HPLC)
别名:
Ala-Pro-Leu-Glu-Pro-Met-Tyr-Pro-Gly-Asp-Tyr-Ala-Thr-His-Glu-Gln-Arg-Ala-Gln-Tyr-Glu-Thr-Gln-Leu-Arg-Arg-Tyr-Ile-Asn-Thr-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
assay
≥95% (HPLC)
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Gene Information
rat ... Ppy(24677)
Biochem/physiol Actions
Agonist at Y4 neuropeptide Y receptors.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Helen M Cox
Autonomic neuroscience : basic & clinical, 133(1), 76-85 (2006-12-05)
This paper reviews the cellular localisation, mechanisms of release and intestinal absorptive actions of neuropeptide Y and its related peptides, peptide YY, pancreatic polypeptide and major fragments NPY(3-36) and PYY(3-36). While NPY is commonly found in inhibitory enteric neurons that
Amanda Sainsbury et al.
Neuropeptides, 44(3), 261-268 (2010-02-02)
Gut-derived peptides are known to regulate food intake by activating specific receptors in the brain, but the target nuclei and neurons influenced are largely unknown. Here we show that peripherally administered pancreatic polypeptide (PP) stimulates neurons in key nuclei of
Shu Lin et al.
PloS one, 4(12), e8488-e8488 (2009-12-31)
Pancreatic polypeptide (PP) is a potent anti-obesity agent known to inhibit food intake in the absence of nausea, but the mechanism behind this process is unknown. Here we demonstrate that in response to i.p. injection of PP in wild type
Ryuichi Moriya et al.
European journal of pharmacology, 627(1-3), 258-264 (2009-10-13)
Pancreatic polypeptide is released mainly from the pancreas, and is thought to be one of the major endogenous agonists of the neuropeptide Y Y(4) receptor. Pancreatic polypeptide has been shown to stimulate colonic muscle contraction, but whether pancreatic polypeptide has
M S Parker et al.
Peptides, 32(2), 258-265 (2010-12-04)
Non-specific binding of Y receptor agonists to intact CHO cells, and to CHO cell or rat brain particulates, is much greater for human neuropeptide Y (hNPY) compared to porcine peptide Y (pPYY), and especially relative to human pancreatic polypeptide (hPP).
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