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经验公式(希尔记法):
C5H12N2O
化学文摘社编号:
分子量:
116.16
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.05
产品名称
N-Nitrosoethylisopropylamine, analytical standard
SMILES string
N(N=O)(C(C)C)CC
InChI
1S/C5H12N2O/c1-4-7(6-8)5(2)3/h5H,4H2,1-3H3
InChI key
VGGZTNNNXAUZLB-UHFFFAOYSA-N
grade
analytical standard
assay
≥99%
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Application
N-Nitrosoethylisopropylamine may be used as an analytical reference standard for the determination of several nitrosamines in large volume parenteral (LVP) drug products using liquid chromatography-mass spectrometry (LC/MS/MS).
General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosoethylisopropylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosoethylisopropylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
150.6 °F - (calculated)
flash_point_c
65.9 °C - (calculated)
法规信息
新产品
此项目有
Development and Validation of a Sensitive LC-MS/MS Method for Simultaneous Determination of Several Nitrosamines in Large Volume Parenteral
Journal of AOAC (Association of Official Analytical Chemists) International, qsaf031-qsaf031 (2025)
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