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Merck
CN

67661

N-Nitrosoethylisopropylamine

analytical standard

别名:

N-Ethyl-N-nitroso-2-propanamine, EIPNA, NEIPA

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关于此项目

经验公式(希尔记法):
C5H12N2O
化学文摘社编号:
分子量:
116.16
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.05
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产品名称

N-Nitrosoethylisopropylamine, analytical standard

SMILES string

N(N=O)(C(C)C)CC

InChI

1S/C5H12N2O/c1-4-7(6-8)5(2)3/h5H,4H2,1-3H3

InChI key

VGGZTNNNXAUZLB-UHFFFAOYSA-N

grade

analytical standard

assay

≥99%

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

Quality Level

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Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Application

N-Nitrosoethylisopropylamine may be used as an analytical reference standard for the determination of several nitrosamines in large volume parenteral (LVP) drug products using liquid chromatography-mass spectrometry (LC/MS/MS).

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosoethylisopropylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

pictograms

Health hazardExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

150.6 °F - (calculated)

flash_point_c

65.9 °C - (calculated)

法规信息

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分析证书(COA)

Lot/Batch Number

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Development and Validation of a Sensitive LC-MS/MS Method for Simultaneous Determination of Several Nitrosamines in Large Volume Parenteral
Journal of AOAC (Association of Official Analytical Chemists) International, qsaf031-qsaf031 (2025)

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