67681
N-Nitrosodiisopropylamine
analytical standard
别名:
N-Isopropyl-N-nitrosoisopropylamine, DIPNA, NDIP
SMILES string
N(N=O)(C(C)C)C(C)C
InChI
1S/C6H14N2O/c1-5(2)8(7-9)6(3)4/h5-6H,1-4H3
InChI key
AUIKJTGFPFLMFP-UHFFFAOYSA-N
grade
analytical standard
assay
≥99%
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
Quality Level
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General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodiisopropylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosodiisopropylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
Application
N-Nitrosodiisopropylamine may be used as an analytical reference standard for the determination of several nitrosamines in large volume parenteral (LVP) drug products using liquid chromatography-mass spectrometry (LC/MS/MS).
Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Development and Validation of a Sensitive LC-MS/MS Method for Simultaneous Determination of Several Nitrosamines in Large Volume Parenteral
Jost L, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, qsaf031-qsaf031 (2025)
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