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Merck
CN

67694

Supelco

N-Nitroso-N-methyl-4-aminobutyric acid

analytical standard

别名:

4-(Methylnitrosoamino)butanoic acid, N-Methyl-N-(3-carboxypropyl)nitrosamine

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关于此项目

经验公式(希尔记法):
C5H10N2O3
化学文摘社编号:
分子量:
146.14
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥99%

保质期

limited shelf life, expiry date on the label

制造商/商品名称

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

技术

HPLC: suitable
gas chromatography (GC): suitable

包装形式

neat

储存温度

−20°C

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一般描述

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitroso-N-methyl-4-aminobutyric acid is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

应用

N-Nitroso-N-methyl-4-aminobutyric acid may be used as an analytical reference standard for the determination of nitrosamine impurities in sartan drugs using liquid chromatography-mass spectrometry (LC/MS/MS).

分析说明

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Health hazard

警示用语:

Warning

危险声明

危险分类

Carc. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of genotoxic impurity N-Nitroso-N-methyl-4-aminobutyric acid in four Sartan substances through using liquid chromatography-tandem mass spectrometry
Xie B, et al.
Molecules (Basel), 27, 7498-7498 (2022)

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