InChI key
ZKXDGKXYMTYWTB-UHFFFAOYSA-N
InChI
1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2
SMILES string
O=NN1CCOCC1
grade
analytical standard
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
Quality Level
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General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosomorpholin (CAS 59-89-2) is a non‑intentionally added substance (NIAS), typically formed by nitrosation of secondary amines in polymers, adhesives, inks, or elastomers. It is not deliberately used as a monomer or additive; occurrences are trace‑level and process‑dependent. Analytical testing focuses on trace identification and quantification, root‑cause analysis, and trend monitoring under worst‑case time/temperature/simulant conditions to support risk assessment and compliance. This analytical standard is utilized in chromatographic and spectrometric techniques for the detectionof nitrosamines in chemical, pharmaceutical, food and environmental matrices.
Discover our portfolio of nitrosamine reference materials
N-Nitrosomorpholin (CAS 59-89-2) is a non‑intentionally added substance (NIAS), typically formed by nitrosation of secondary amines in polymers, adhesives, inks, or elastomers. It is not deliberately used as a monomer or additive; occurrences are trace‑level and process‑dependent. Analytical testing focuses on trace identification and quantification, root‑cause analysis, and trend monitoring under worst‑case time/temperature/simulant conditions to support risk assessment and compliance. This analytical standard is utilized in chromatographic and spectrometric techniques for the detectionof nitrosamines in chemical, pharmaceutical, food and environmental matrices.
Discover our portfolio of nitrosamine reference materials
Application
N-Nitrosomorpholine may be used as an analytical reference standard for the determination of nitrosamines in drinking water using ultra-high-pressure liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS).
Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
target_organs
Liver
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Muta. 2 - STOT RE 1
法规信息
监管及禁止进口产品
此项目有
Ultratrace-level determination of N-Nitrosodimethylamine, N-Nitrosodiethylamine, and N-Nitrosomorpholine in waters by solid-phase extraction followed by liquid chromatography-tandem mass spectrometry
Kadmi Y, et al.
open chemistry, 12, 928-936 (2014)
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