67963
N-亚硝基甲基苯胺 (NMPA)
analytical standard
别名:
N-Nitrosomethylphenylamine (NMPA), N-Methyl-N-nitrosoaniline, N-Methyl-N-nitrosobenzenamine, N-Methyl-N-phenylnitrosamine, NMPA
SMILES string
N(N=O)(C)c1ccccc1
InChI
1S/C7H8N2O/c1-9(8-10)7-5-3-2-4-6-7/h2-6H,1H3
InChI key
MAXCWSIJKVASQC-UHFFFAOYSA-N
grade
analytical standard
assay
≥99%
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
Quality Level
General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosomethylphenylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosomethylphenylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
Application
N-Nitrosomethylphenylamine may be used as an analytical reference standard for the quantification of nitrosamines in olmesartan tablets using liquid chromatography tandem mass spectrometry (LC-MS/MS).
Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
A multianalyte LC-MS/MS method for accurate quantification of Nitrosamines in Olmesartan tablets
Pawar, et al.
Journal of Chromatography A, 1732, 465176-465176 (2024)
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