68088
N-Nitrosomethylethylamine
analytical standard
别名:
N-Nitroso-N-methylethylamine, NMEA
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关于此项目
经验公式（希尔记法）:
C3H8N2O
化学文摘社编号:
分子量:
88.11
UNSPSC Code:
12352116
NACRES:
NA.24
MDL number:
产品名称
N-Nitrosomethylethylamine, analytical standard
SMILES string
N(N=O)(CC)C
InChI key
RTDCJKARQCRONF-UHFFFAOYSA-N
grade
analytical standard
assay
≥95%
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Application
N-Nitrosomethylethylamine may be used as an analytical reference standard for the quantification of nitrosamine impurities in metformin drug products using liquid chromatography-high resolution mass spectrometry (LC-HRMS).
General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosomethylethylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosomethylethylamine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
170.1 °F - closed cup
flash_point_c
76.7 °C - closed cup
法规信息
新产品
此项目有
A comprehensive approach for N-nitrosamine determination in pharmaceuticals using a novel HILIC-based solid phase extraction and LC-HRMS
Parfant, et al.
Talanta, 282, 126752-126752 (2025)
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