等级
analytical standard
质量水平
保质期
limited shelf life, expiry date on the label
制造商/商品名称
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
技术
HPLC: suitable
gas chromatography (GC): suitable
折射率
n20/D 1.489 (lit.)
沸点
214 °C (lit.)
密度
1.085 g/mL at 25 °C (lit.)
包装形式
neat
储存温度
2-8°C
SMILES字符串
O=NN1CCCC1
InChI
1S/C4H8N2O/c7-5-6-3-1-2-4-6/h1-4H2
InChI key
WNYADZVDBIBLJJ-UHFFFAOYSA-N
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一般描述
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosopyrrolidine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosopyrrolidine is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
应用
N-Nitrosopyrrolidine may be used as an analytical reference standard for the quantification of volatile nitrosamines in cosmetics using gas chromatography/mass spectrometry (GC/MS).
生化/生理作用
在小鼠中诱发肝细胞癌和肺腺瘤。形成主要导致 A：T 到 G：C 突变的 DNA 加合物。
分析说明
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
208.4 °F - closed cup
闪点(°C)
98 °C - closed cup
法规信息
新产品
此项目有
Identification and quantification of seven volatile n-nitrosamines in cosmetics using gas chromatography/chemical ionization--mass spectrometry coupled with head space-solid phase microextraction
Choi Na, et al.
Talanta, 148, 69-74 (2016)
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