产品名称
硫酸羟氯喹, British Pharmacopoeia (BP) Reference Standard
InChI
1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
SMILES string
OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI key
JCBIVZZPXRZKTI-UHFFFAOYSA-N
grade
pharmaceutical primary standard
agency
BP
API family
hydroxychloroquine
form
solid
shelf life
limited shelf life, expiry date on the label
packaging
pkg of 100 mg
manufacturer/tradename
BP
color
off-white
mp
238-241 °C
solubility
water: soluble
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
shipped in
ambient
storage temp.
2-8°C
Gene Information
human ... TLR7(51284), TLR9(54106)
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Biochem/physiol Actions
硫酸羟氯喹是一种抗炎（通过肿瘤坏死因子）、疾病调节抗风湿药物（DMARD）和血红素聚合酶抑制剂。
硫酸羟氯喹是一种抗炎（通过肿瘤坏死因子）、疾病调节抗风湿药物（DMARD）和血红素聚合酶抑制剂。 它可用于治疗疟疾。
Application
Hydroxychloroquine sulfate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Hydroxychloroquine Tablets
Also used in monographs such as:
General description
Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).
Packaging
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Famotidine
British Pharmacopeia
British Pharmacopoeia, 44(12), 1000-1004 (2020)
Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
Fuzery AK, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Charlier B,et al.
Biomedical Chromatography, 32(8), e4258-e4258 (2018)
QUALITY BY DESIGN IN THE DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD BY ULTRAVIOLET-VISIBLE SPECTROPHOTOMETRY FOR QUANTIFICATION OF HYDROXYCHLOROQUINE SULFATE
Ferraz LRM, et al.
International Journal of Pharmaceutical Sciences and Research, 5(11), 4666-4666 (2014)
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