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Merck
CN

BP894

布地奈德杂质标准品

British Pharmacopoeia (BP) Reference Standard

别名:

布地奈德

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关于此项目

经验公式（希尔记法）:
C25H34O6
化学文摘社编号:
51333-22-3
分子量:
430.53
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00083259

主要文件

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InChI

1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(CCC)O[C@@]45C(=O)CO

InChI key

VOVIALXJUBGFJZ-KWVAZRHASA-N

grade

pharmaceutical primary standard

API family

budesonide

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

mixture

storage temp.

−20°C

Gene Information

human ... NR3C1(2908)

相关类别

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Budesonide impurity standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Budesonide Aqueous Nasal Spray

    • Biochem/physiol Actions

    Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.
    Second generation glucocorticoid with low systemic absorption; anti-inflammatory agent; inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein.

    Packaging

    Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    pictograms

    Health hazardExclamation mark
    GHS08,GHS07

    signalword

    Danger

    Hazard Classifications

    Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

    target_organs

    Adrenal gland

    存储类别

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    法规信息

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    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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