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Merck
CN

Y0002407

布立西坦

European Pharmacopoeia (EP) Reference Standard

别名:

Brivaracetam, (αS,4R)-α-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide, (2S)-2-[(4R)-2-Oxo-4-propylpyrrolidin-1-yl]butanamide, (S)-2-((R)-2-Oxo-4-propylpyrrolidin-1-yl)butanamide, UCB 34714, UCB-34714, UCB34714

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关于此项目

经验公式(希尔记法):
C11H20N2O2
化学文摘社编号:
分子量:
212.29
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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grade

pharmaceutical primary standard

agency

BP

manufacturer/tradename

EDQM

application(s)

pharmaceutical

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. Compendial materials should be used for the purpose described in the appropriate monograph unless otherwise authorized by the National Competent Authority. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

e.g. pharmaceutical (small molecule)

Biochem/physiol Actions

Brivaracetam shows approximately 10 times greater potency than levetiracetam (Keppra)*; pIC50 at LBS = 7.0; inhibits audiogenic seizures in seizure-prone mice (ED50 = 14 μmol/kg) and is also effective in other animal models of epilepsy. Brivaracetam is used as an anticonvulsant (antiepileptic) for seizure treatment.
Orally active levetiracetam analog with higher synaptic vesicle protein 2A (SV2A) affinity and >10 times greater in vivo antiseizure efficay.

Packaging

Unit quantity: 160mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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