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经验公式（希尔记法）:
C23H30O3
化学文摘社编号:
分子量:
354.48
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
SMILES string
O(C)c1c(c(c(c(c1)C)\C=C\C(=C\C=C\C(=C\C(=O)OCC)\C)\C)C)C
InChI
1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+
InChI key
HQMNCQVAMBCHCO-DJRRULDNSA-N
grade
pharmaceutical primary standard
API family
acitretin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Acitretin Related Compound B USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Acitretin
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
N Ishida et al.
Clinical and experimental dermatology, 34(3), 385-389 (2008-12-17)
Photodynamic therapy (PDT) with 5-aminolaevulinic acid (5-ALA) is a noninvasive and effective treatment for superficial skin cancers. Etretinate, a derivate of vitamin A, with the chemical formula ethyl(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nona-tetraenoate, has been reported to have antitumour effects and to regulate the proliferation
Etretinate combined with low-dose prednisolone for an aged patient with adult T-cell leukaemia/lymphoma.
K Senba-Nakata et al.
Clinical and experimental dermatology, 35(4), e153-e154 (2009-11-21)
Psoriasis verrucosa.
Kenya Wakamatsu et al.
The Journal of dermatology, 37(12), 1060-1062 (2010-11-19)
Photoleukomelanoderma possibly caused by etretinate in a patient with psoriasis.
Mariko Seishima et al.
Acta dermato-venereologica, 90(1), 85-86 (2010-01-29)
Hyung-Doo Park et al.
Transfusion, 48(11), 2395-2400 (2008-07-29)
Acitretin and etretinate are potentially teratogenic. Many people taking acitretin for psoriasis have donated blood during the deferral period in Korea. Therefore, many of the blood products from these donors treated with acitretin have been circulated in Korea. A high-performance
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