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Merck
CN

1042408

USP

阿加曲班 一水合物

United States Pharmacopeia (USP) Reference Standard

别名:

(2R,4R)-1-[(2S)-5-[(氨基亚氨基甲基)氨基]-1-氧代-2- [[(1,2,3,4-四氢-3-甲基-8-喹啉基)磺酰基] 氨基] 戊基]-4-甲基-2-哌啶羧酸, 精氨酸, 质量受权人

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关于此项目

经验公式(希尔记法):
C23H36N6O5S · H2O
化学文摘社编号:
分子量:
526.65
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

agency

USP

API family

argatroban

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(NC(CCCNC(=N)N)C(=O)N3[C@H](C[C@@H](CC3)C)C(=O)O)c1c2c(ccc1)CC(CN2)C.O

InChI

1S/C23H36N6O5S.H2O/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19;/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26);1H2/t14-,15?,17?,18-;/m1./s1

InChI key

AIEZTKLTLCMZIA-LINCPPCXSA-N

General description

Find answers to frequently asked questions on USP products in USP FAQs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Argatroban USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Argatroban Injection

Biochem/physiol Actions

阿加曲班是一种强效、选择性、单价凝血酶直接抑制剂。与既结合活性站点又结合外部位点 1 的二价 DTI(水蛭素及其类似物)相比,它只结合凝血酶的活性点位(因此属于单价)而直接抑制凝血酶。
阿加曲班是一种强效、选择性、直接的凝血酶抑制剂,也是一种临床抗凝药。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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