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1066009

USP

倍他米松

Name: 倍他米松
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

9α-氟-11β,17α,21-三羟基-16β-甲基孕甾-1,4-二烯-3,20-二酮, 9α-氟-16β-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮, 9α-氟-16β-甲基泼尼松龙

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关于此项目

经验公式（希尔记法）:

C₂₂H₂₉FO₅

化学文摘社编号:

378-44-9

分子量:

392.46

NACRES:

NA.24

PubChem Substance ID:

329748930

UNSPSC Code:

41116107

MDL number:

MFCD00062969

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属性

biological source

synthetic

grade

pharmaceutical primary standard

agency

USP

vapor pressure

<0.0000001 kPa ( 25 °C)

API family

betamethasone

packaging

pkg of 200 mg

manufacturer/tradename

USP

color

white to off-white

mp

235-237 °C (lit.), 447.8-473 °F (231—245°C; decomposes)

solubility

acetone: sparingly soluble, chloroform: very slightly soluble, ethanol: sparingly soluble, ether: very slightly soluble, methanol: sparingly soluble, water: insoluble

density

0.305 g/cm³ at 25 °C (77°F)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChI key

UREBDLICKHMUKA-DVTGEIKXSA-N

Gene Information

human ... NR3C1(2908)

说明

General description

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Betamethasone Acetate
Betamethasone Oral Solution
Betamethasone Valerate Cream
Betamethasone Valerate Lotion
Betamethasone Valerate Ointment
Dexamethasone

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08

signalword

Danger

hcodes

H360FD,H373

pcodes

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B - STOT RE 2

target_organs

Liver,Kidney,Endocrine system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Betamethasone

USP43-NF38: United States Pharmacopeia and National Formulary

United States Pharmacopeia, 44(1), 541-541 (2020)

Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC

Santos-Montes A, et al.

Chromatographia, 39(9-10), 539-542 (1994)

Analysis of betamethasone and its organic esters in pharmaceutical products

Graham RE, et al.

Journal of Pharmaceutical Sciences, 67(3), 360-363 (1978)

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全球贸易项目编号

货号	GTIN
1066009-200MG	04061838674265