1075305
USP
Bisdesmethoxycurcumin
United States Pharmacopeia (USP) Reference Standard
别名:
1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
等级
pharmaceutical primary standard
API类
curcumin
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
−20°C
SMILES字符串
Oc1ccc(cc1)\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)O
InChI
1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+
InChI key
PREBVFJICNPEKM-YDWXAUTNSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Bisdesmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Curcuminoids
- Curcuminoids Capsules
- Curcuminoids Tablets
- Powdered Turmeric
- Powdered Turmeric Extract
- Turmeric
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance.
J R Cashman et al.
Neuro-degenerative diseases, 10(1-4), 274-276 (2011-12-14)
Neurodegenerative diseases are associated with accumulation of modified proteins or peptides including amyloid-β (Aβ) in Alzheimer's disease (AD), and misfolded superoxide dismutase-1 (SOD-1) in amyotrophic lateral sclerosis (ALS). Clearance of Aβ or SOD-1 by the innate immune system may be
Y-L Liu et al.
Current cancer drug targets, 11(9), 1098-1110 (2011-09-22)
Hypermethylation of the Wnt inhibitory factor-1 (WIF-1) promoter has been implicated in the overactivation of the Wnt pathway in human lung cancer. Curcuminoids exert anti-cancer effects and have been reported to act as hypomethylating agents. Previously, we have investigated and
Ying-Bo Li et al.
Pharmacological reports : PR, 65(3), 700-709 (2013-08-21)
Bisdemethoxycurcumin (BDMC) is a natural derivative of curcumin present in the phenolic components extracted from the dried rhizome of Curcuma longa L. BDMC demonstrated potential chemotherapeutic activities but the underlying mechanisms have not been fully clarified. In the present study
Yinan Hua et al.
Molecular nutrition & food research, 57(9), 1611-1618 (2013-04-05)
A key event in the development of plaque in the arteries is the migration and proliferation of smooth muscle cells (SMCs) from the media to the intima of the blood vessel. This study was conducted to evaluate the effects of
Dong-Chan Kim et al.
BMB reports, 45(4), 221-226 (2012-04-26)
Curcumin, a polyphenol responsible for the yellow color of the curry spice turmeric, possesses antiinflammatory, antiproliferative and antiangiogenic activities. However, anticoagulant activities of curcumin have not been studied. Here, the anticoagulant properties of curcumin and its derivative (bisdemethoxycurcumin, BDMC) were
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