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主要文件

1076192

USP

牛血清白蛋白 来源于牛血清

United States Pharmacopeia (USP) Reference Standard

别名:

BSA, 牛白蛋白, 牛血清白蛋白

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About This Item

CAS Number:
9048-46-8
MDL编号:
MFCD00130384
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

表单

liquid

分子量

~66 kDa

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

single component solution

储存温度

2-8°C

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一般描述

Bovine Serum Albumin (BSA) is a globular protein derived from bovine blood plasma. It is widely utilized as a standard in protein quantitation assays due to its stability and lack of interference with the assay components.​

The USP BSA for Protein Quantitation standard serves as a calibration reference in assays such as the Bradford and Bicinchoninic Acid (BCA) assays, ensuring accurate and reproducible measurement of protein concentrations in various research and clinical applications.

The USP biologics proteins category provides critical standards and reference materials necessary for the development and manufacturing of therapeutic proteins. These proteins, which can be naturally derived or genetically engineered, are essential in treating various diseases and conditions, ensuring that they meet quality, safety, and efficacy standards.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

应用

BSA for protein quantitation USP reference standard in specified compendial tests and assays.

Also used to prepare standard and suitability standard solutions during the determination of total protein in pharmaceutical drug substances and products according to the United States Pharmacopeia (USP) general chapter.

生化/生理作用

BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。

制备说明

血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。 血清白蛋白可在采用Cohn′法的第五乙醇分级中发现。 从此，有些人便开始使用“Fraction V”这一术语来描述血清白蛋白，无论使用的是什么制备方法。 也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白，而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白，包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。 更多的纯化步骤包括结晶或木炭过滤。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Shipping condition: wet ice
This product is part of the USP Biologics program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.Shipping condition: wet ice
Sales restrictions may apply.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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