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1096779

USP

Casticin

Name: Casticin
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

3′,5-Dihydroxy-3,4′,6,7-tetramethoxyflavone, 3,4′,6,7-Tetra-O-methylquercetagetin, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one, Quercetagetin 3,4′,6,7-tetramethyl ether, Vitexicarpin

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关于此项目

经验公式（希尔记法）:

C₁₉H₁₈O₈

化学文摘社编号:

479-91-4

分子量:

374.34

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329749248

MDL number:

MFCD00210481

Beilstein/REAXYS Number:

1300392

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属性

grade

pharmaceutical primary standard

API family

casticin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(cc1O)C2=C(OC)C(=O)c3c(O)c(OC)c(OC)cc3O2

InChI

1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3

InChI key

PJQLSMYMOKWUJG-UHFFFAOYSA-N

说明

General description

Casticin is a flavonoid, widely used as an anti-inflammatory agent. It has anti-tumor properties and is considered to be a potent immunomodulatory and cytotoxic compound.

Application

It was may be used as reference standard to compare retention time and ion peaks in plant extracts during GC/MS analysis to quantify Casticin and artemetin.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Casticin induces leukemic cell death through apoptosis and mitotic catastrophe.

Jia-Kun Shen et al.

Annals of hematology, 88(8), 743-752 (2009-01-14)

Casticin, a component from Vitex rotundifolia, widely used as an anti-inflammatory agent in Chinese traditional medicine, was reported to have anti-tumor activities. This study aims to examine the anti-leukemic activity of casticin on leukemia cells and its molecular mechanism. Cell

The flavonoids casticin and artemetin are poorly extracted and are unstable in an Artemisia annua tea infusion.

Pamela J Weathers et al.

Planta medica, 78(10), 1024-1026 (2012-06-08)

A number of flavonoids including casticin and artemetin from Artemisia annua have shown synergism with artemisinin against Plasmodium falciparum, but it is unclear if the flavonoids are also extracted into a tea infusion of the plant. Using a tea infusion

Isolation and immunomodulatory properties of a flavonoid, casticin from Vitex agnus-castus.

M Ahmed Mesaik et al.

Phytotherapy research : PTR, 23(11), 1516-1520 (2009-05-15)

Casticin (1), a flavonoid isolated from the aerial parts of Vitex agnus-castus, was found to be a potent immunomodulatory and cytotoxic compound. The activity was tested in vitro for chemiluminescence, chemotaxis, T-cell proliferation and cytotoxicity. Casticin (1) exhibited a significant

全球贸易项目编号

货号	GTIN
1096779-25MG	04061833841921