InChI
1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)
SMILES string
ClC(C=C1)=CC2=C1C(NC(CCCNCC)C)=CC=N2
InChI key
MCYUUUTUAAGOOT-UHFFFAOYSA-N
biological source
synthetic
grade
pharmaceutical primary standard
agency
USP
API family
chloroquine
form
powder
packaging
pkg of 15 mg
manufacturer/tradename
USP
storage condition
protect from light
color
tan
bp
343.4-347 °F (173—175°C; 845.06°F )
mp
176-215.6 °F (80—102°C)
solubility
chloroform: soluble, dichloromethane: soluble
density
1.14 g/cm3
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
Chloroquine Related Compound D is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.
Application
Chloroquine Related Compound D USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Chloroquine Phosphate
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
HPLC with ultraviolet detection for the determination of chloroquine and desethylchloroquine in whole blood and finger-prick capillary blood dried on filter paper
Cheomung A and Na-Bangchang K
Journal of Pharmaceutical and Biomedical Analysis, 55(5), 1031-1040 (2011)
An HPLC method with diode array detector for the simultaneous quantification of chloroquine and desethylchloroquine in plasma and whole blood samples from Plasmodium vivax patients in Vietnam, using quinine as an internal standard
Van Pham T, et al.
Biomedical Chromatography, 30(7), 1104-1111 (2016)
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)
Chloroquine Phosphate USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 959-959 (2020)
实验方案
Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.
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