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经验公式(希尔记法):
C28H30N2O2 · HBr
化学文摘社编号:
分子量:
507.46
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
产品名称
达非那新氢溴酸盐 氢溴酸盐, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1
SMILES string
O=C(N)C([C@H]1CN(CCC2=CC=C(OCC3)C3=C2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5.Br
InChI key
UQAVIASOPREUIT-VQIWEWKSSA-N
API family
darifenacin
form
solid
manufacturer/tradename
USP
application(s)
pharmaceutical
Gene Information
human ... CHRM2(1129), CHRM3(1131)
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Biochem/physiol Actions
氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂,对阻断M3毒蕈碱乙酰胆碱受体具有选择性。
氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂,对阻断M3毒蕈碱乙酰胆碱受体具有选择性,M3毒蕈碱乙酰胆碱受体主要负责膀胱肌肉的收缩。 氢溴酸达非那新对M3的亲和力分别比M1和M5高9和12倍,对M3的亲和力比M2和M4分别高59倍。 达非那新在临床上可用于治疗尿失禁和膀胱过度活动症。
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Darifenacin hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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