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Merck
CN

1164200

USP

达非那新氢溴酸盐 氢溴酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

UK 88525–04, (3S)-1- [2-(2,3-二氢-5-苯并呋喃基)乙基]-α,α-二苯基-3-吡咯烷乙酰胺 氢溴酸盐

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关于此项目

经验公式(希尔记法):
C28H30N2O2 · HBr
化学文摘社编号:
分子量:
507.46
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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产品名称

达非那新氢溴酸盐 氢溴酸盐, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1

SMILES string

O=C(N)C([C@H]1CN(CCC2=CC=C(OCC3)C3=C2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5.Br

InChI key

UQAVIASOPREUIT-VQIWEWKSSA-N

API family

darifenacin

form

solid

manufacturer/tradename

USP

application(s)

pharmaceutical

Gene Information

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Biochem/physiol Actions

氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂,对阻断M3毒蕈碱乙酰胆碱受体具有选择性。
氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂,对阻断M3毒蕈碱乙酰胆碱受体具有选择性,M3毒蕈碱乙酰胆碱受体主要负责膀胱肌肉的收缩。 氢溴酸达非那新对M3的亲和力分别比M1和M5高9和12倍,对M3的亲和力比M2和M4分别高59倍。 达非那新在临床上可用于治疗尿失禁和膀胱过度活动症。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Darifenacin hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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