biological source
synthetic
grade
pharmaceutical primary standard
agency
USP
vapor pressure
<0.0000001 kPa ( 25 °C)
API family
desoximetasone
form
powder
packaging
pkg of 200 mg
manufacturer/tradename
USP
storage condition
protect from light
color
white
solubility
acetone: freely soluble, alcohol: freely soluble, benzene: slightly soluble, chloroform: freely soluble, ether: slightly soluble, water: insoluble
application(s)
pharmaceutical (small molecule)
SMILES string
[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
InChI
1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
InChI key
VWVSBHGCDBMOOT-IIEHVVJPSA-N
Gene Information
human ... NR3C1(2908)
General description
Desoximetasone is a topical corticosteroid known to modify the functions of leukocytes that are mainly responsible for skin infections, inflammation and allergies.
Application
Desoximetasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Desoximetasone Cream
- Desoximetasone Gel
- Desoximetasone Ointment
- Dexamethasone
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2 - Skin Sens. 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Development and Validation of RP-HPLC Method for Desoximetasone in Bulk and Cream Formulation
Gorle A, et al.
Journal of Drug Delivery and Therapeutics, 9(3), 154-159 (2019)
S Vladimirov et al.
Journal of pharmaceutical and biomedical analysis, 14(8-10), 947-950 (1996-06-01)
The proposed method is based on coloured hydrazone formation with 1,4-dihydrazinophthalazine as a reagent. Heating at 85 degrees C for 2 h was found necessary to ensure optimal hydrazone formation in the presence of hydrochloric acid. The yellow hydrazone product
Topical corticosteroids: mechanisms of action.
Kragballe, K
Acta Dermato-Venereologica. Supplementum, 151(3), 7-7 (1989)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1173508-200MG | 04061833849798 |