1229001
USP
氟哌利多
United States Pharmacopeia (USP) Reference Standard
别名:
1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone
等级
pharmaceutical primary standard
API类
droperidol
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)N3C(=O)Nc4ccccc34
InChI
1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)
InChI key
RMEDXOLNCUSCGS-UHFFFAOYSA-N
基因信息
human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
E S Brown et al.
Clinical neuropharmacology, 21(5), 316-318 (1998-10-28)
There is little information in the literature concerning the use of droperidol in psychiatry. This article presents three cases in which extremely agitated and treatment-refractory persons with mixed mania derived benefit from droperidol administered orally. Symptomatic improvement, including decreased agitation
R A Chambers et al.
The Journal of clinical psychiatry, 60(10), 664-667 (1999-11-05)
As admission criteria to inpatient units become more focused on patient safety and behavioral instability, primary treatment often requires use of medications that need to be quick, safe, and effective for control of agitation. This article reviews the evidence that
Droperidol- and ondansetron-induced life-threatening arrhythmias.
Jasmine Patel
Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association, 39(4), 393-394 (2013-07-09)
Krzysztof Tracz et al.
British journal of clinical pharmacology, 79(4), 669-676 (2014-10-09)
Drugs used for postoperative nausea and vomiting prophylaxis are believed to provoke torsadogenic changes in cardiac repolarization. The aim of this study was to assess the effect of small doses of droperidol on the parameters of cardiac repolarization, including the
I Henzi et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 47(6), 537-551 (2000-06-30)
To estimate the efficacy and harm produced by droperidol in the prevention of postoperative nausea and vomiting (PONV). Systematic search (MEDLINE, EMBASE, Cochrane library, hand-searching, bibliographies, all languages, up to May 1999) for randomised comparisons of droperidol with placebo in
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