产品名称
雌素酮, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1
SMILES string
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O
InChI key
DNXHEGUUPJUMQT-CBZIJGRNSA-N
grade
pharmaceutical primary standard
API family
estrone
manufacturer/tradename
USP
mp
258-260 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... ESR1(2099)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Estrone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Conjugated Estrogens
- Conjugated Estrogens Tablets
- Esterified Estrogens
- Esterified Estrogens Tablets
- Estradiol
- Estradiol and Norethindrone Acetate Tablets
- Estradiol Tablets
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Lact. - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Robert E Nelson et al.
Clinical chemistry, 50(2), 373-384 (2003-12-06)
Estradiol (E2) and estrone (E1) measurements form an integral part of the assessment of female reproductive function and have expanding roles in other fields. However, many E1 and E2 immunoassays have limited functional sensitivity, suffer from cross-reactivity, and display poor
Fluorometric determination of plasma 11-hydroxycorticosteroids. II. Studies on the specificity of the method.
L E Mejer et al.
Clinical chemistry, 19(7), 718-724 (1973-07-01)
Xavier Remesar et al.
Medicinal research reviews, 32(6), 1263-1291 (2011-02-03)
Oleoyl-estrone (OE) is a powerful slimming agent that is also present in plasma and adipose tissue, where it is synthesized. It acts through the formation of a derivative W. OE effects (and W levels) are proportional to the dose. OE
Eva Fetter et al.
Aquatic toxicology (Amsterdam, Netherlands), 154, 221-229 (2014-06-14)
Xenoestrogens may persist in the environment by binding to sediments or suspended particulate matter serving as long-term reservoir and source of exposure, particularly for organisms living in or in contact with sediments. In this study, we present for the first
Shanshan Zhao et al.
Breast cancer research : BCR, 16(2), R30-R30 (2014-03-29)
Paradoxically, a breast cancer risk reduction with conjugated equine estrogens (CEE) and a risk elevation with CEE plus medroxyprogesterone acetate (CEE + MPA) were observed in the Women's Health Initiative (WHI) randomized controlled trials. The effects of hormone therapy on serum sex
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