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经验公式（希尔记法）:
C17H18F3NO · HCl
化学文摘社编号:
分子量:
345.79
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
氟西汀 盐酸盐, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
SMILES string
CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl
InChI key
GIYXAJPCNFJEHY-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
fluoxetine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... SLC6A4(6532)
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Biochem/physiol Actions
选择性羟色胺再摄取抑制剂；抗抑郁剂。
Legal Information
经 Eli Lilly and Company 授权销售。
Prozac is a registered trademark of Eli Lilly and Co.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Fluoxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Fluoxetine Tablets
- Fluoxetine Delayed-Release Capsules
- Olanzapine and Fluoxetine Capsules
- Fluoxetine Oral Solution
- Fluoxetine Capsules
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
R J Gonzalez-Rothi et al.
Chest, 107(6), 1763-1765 (1995-06-01)
We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we
Kristie T Ota et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(3), 711-718 (2014-09-03)
Major depressive disorder (MDD) is a debilitating and widespread illness that exerts significant personal and socioeconomic consequences. Recent genetic and brain-imaging studies suggest that bicaudal C homolog 1 gene (BICC1), which codes for an RNA-binding protein, may be associated with
Sean C Godar et al.
Journal of psychiatric research, 56, 1-9 (2014-06-03)
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alterations, including perseverative behaviors and
Rody Kingston et al.
PLoS genetics, 17(11), e1009885-e1009885 (2021-11-05)
Molecular insights into the selective vulnerability of retinal ganglion cells (RGCs) in optic neuropathies and after ocular trauma can lead to the development of novel therapeutic strategies aimed at preserving RGCs. However, little is known about what molecular contexts determine
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