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经验公式（希尔记法）:
C12H17N3O4S · H2O
化学文摘社编号:
分子量:
317.36
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
亚胺培南 一水合物, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
SMILES string
O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O
InChI key
GSOSVVULSKVSLQ-JJVRHELESA-N
grade
pharmaceutical primary standard
API family
imipenem
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
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Biochem/physiol Actions
亚胺培南一水合物是广谱 B -内酰胺抗生素。
亚胺培南一水合物是广谱 B -内酰胺抗生素。 它是碳青霉烯类“魔弹”抗生素的一种，用于严重感染。
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Imipenem monohydrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Imipenem
- Imipenem and Cilastatin for Injectable Suspension
- Imipenem and Cilastatin for Injection
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
The deadly impact of extreme drug resistance in Acinetobacter baumannii.
Brad Spellberg et al.
Critical care medicine, 42(5), 1289-1291 (2014-04-17)
Imipenem heteroresistance: high prevalence among Enterobacteriaceae Klebsiella pneumoniae carbapenemase producers.
Carolina Silva Nodari et al.
Journal of medical microbiology, 64(Pt 1), 124-126 (2014-10-30)
Hao-Yuan Lee et al.
Critical care medicine, 42(5), 1081-1088 (2014-01-08)
Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. Retrospective study. All adult ICUs
Bacteremia due to imipenem-resistant Roseomonas mucosa in a child with acute lymphoblastic leukemia.
Anne-Laure Michon et al.
Journal of pediatric hematology/oncology, 36(3), e165-e168 (2013-05-15)
Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial susceptibility pattern varies according to the species. We report the first case of bacteremia due to Roseomonas mucosa in a child
Yi-Jiun Pan et al.
Antimicrobial agents and chemotherapy, 59(2), 1038-1047 (2014-12-03)
Klebsiella pneumoniae is an important human pathogen associated with a variety of diseases, and the prevalence of multidrug-resistant K. pneumoniae (MDRKP) is rapidly increasing. Here we determined the capsular types of 85 carbapenem-resistant K. pneumoniae (CRKP) strains by wzc sequencing
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