产品名称
丙米嗪 盐酸盐, United States Pharmacopeia (USP) Reference Standard
InChI key
XZZXIYZZBJDEEP-UHFFFAOYSA-N
SMILES string
Cl[H].CN(C)CCCN1c2ccccc2CCc3ccccc13
InChI
1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H
grade
pharmaceutical primary standard
API family
imipramine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... SLC6A2(6530), SLC6A4(6532)
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Analysis Note
这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。
Application
盐酸丙咪嗪USP参考标准品，预期用途为USP规定的指定质量测试和检测。也用于USP各论，例如：
- 盐酸丙咪嗪片
- 盐酸丙咪嗪注射液
- 盐酸地昔帕明
- 盐酸氯米帕明
- 盐酸地昔帕明片
- 马来酸曲米帕明
Biochem/physiol Actions
三环类抗抑郁药；抑制 5-羟色胺和去甲肾上腺素转运蛋白；对多巴胺转运蛋白影响很小。
三环类抗抑郁药；抑制血清素和去甲肾上腺素转运蛋白的 Ki 值分别为 7.7 nM 和 67 nM。对多巴胺转运蛋白影响很小（Ki = 25 μM）。
General description
本产品按照现行药典要求提供和指定。所有为支持本产品而提供的信息，包括 SDS 和任何产品信息小册子，均由药典颁发机构制定和发布。如需进一步信息和支持，请访问现行药典网站。
Other Notes
可能适用相应的销售限制。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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