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文件

1356632

USP

酮洛芬

Name: 酮洛芬
Brand: USP

United States Pharmacopeia (USP) Reference Standard

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别名:

2-(3-苯甲酰苯基)丙酸

经验公式（希尔记法）:

C₁₆H₁₄O₃

CAS号:

22071-15-4

分子量:

254.28

MDL编号:

MFCD00055790

PubChem化学物质编号:

329750217

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

ketoprofen

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

基因信息

human ... PTGS1(5742) , PTGS2(5743)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ketoprofen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化/生理作用

非甾体类抗炎化合物，具有COX-1选择性。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

Sales restrictions may apply.

1356643

1356563

1356552

BP668

酮洛芬, British Pharmacopoeia (BP) Reference Standard

BP667

Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

PHR2877

2-(3-苯甲酰基苯基)-丙腈, pharmaceutical secondary standard, certified reference material

PHR2955

PHR3018

象形图

GHS06

警示用语：

Danger

危险声明

H301

预防措施声明

P264 - P270 - P301 + P310 - P405 - P501

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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索取COA

Biowaiver monographs for immediate-release solid oral dosage forms: ketoprofen.

Igor E Shohin et al.

Journal of pharmaceutical sciences, 101(10), 3593-3603 (2012-07-13)

Literature and experimental data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing ketoprofen are reviewed. Ketoprofen's solubility and permeability, its therapeutic use and

4 cases of photocontact dermatitis due to ketoprofen.

M Sugiura et al.

Contact dermatitis, 43(1), 16-19 (2000-07-21)

We report 4 cases of photocontact dermatitis due to ketoprofen, a non-steroidal anti-inflammatory drug derived from propionic acid. We carried out a skin biopsy to examine the amount of ketoprofen in the eruptive skin. We investigated the cross-reactions between tiaprofenic

Photosensitivity to ketoprofen: mechanisms and pharmacoepidemiological data.

H Bagheri et al.

Drug safety, 22(5), 339-349 (2000-06-01)

The topical use of nonsteroidal anti-inflammatory drugs (NSAIDs), widely used for moderate acute and chronic painful conditions, is one of several strategies used to improve the tolerability profile of NSAIDs, particularly with regard to gastric and renal adverse effects. However

Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults.

Jodie Barden et al.

The Cochrane database of systematic reviews, (4)(4), CD007355-CD007355 (2009-10-13)

Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions. Dexketoprofen is the (S)-enantiomer, which is believed to confer analgesia. Theoretically dexketoprofen is expected to provide equivalent analgesia to ketoprofen at half the dose

Clinical pharmacokinetics of ketoprofen and its enantiomers.

F Jamali et al.

Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)

Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the

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酮洛芬