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1370462

USP

氯沙坦钾

Name: 氯沙坦钾
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

2-丁基-4-氯-1-[[2′-(2H-四唑-5-基)[1,1′-联苯]-4-基]甲基]- 1H-咪唑-5-甲醇钾盐, 2-丁基-4-氯-1-{[2′-(1H-四唑-5-yl)(1,1′-联苯)-4-yl]甲基}-1H-咪唑-5-甲醇单钾盐, DuP 753, MK 954, 钾5-(4′-((2-丁基-4-氯-5-(羟甲基)-1H-咪唑-1-基)甲基)-[1,1′-联苯]-2-yl)四唑-1-ide

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选择规格

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关于此项目

经验公式（希尔记法）:

C₂₂H₂₂ClKN₆O

化学文摘社编号:

124750-99-8

分子量:

461.00

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750264

MDL number:

MFCD02092704

Beilstein/REAXYS Number:

5845770

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属性

grade

pharmaceutical primary standard

agency

USP

API family

losartan

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]

InChI

1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1

InChI key

OXCMYAYHXIHQOA-UHFFFAOYSA-N

Gene Information

human ... AGTR1(185)

说明

General description

Losartan potassium is a new drug used for hypertension. It is nonpeptide angiotensin II (AII) receptor antagonist.

Find answers to frequently asked questions on USP products in USP FAQs.

Losartan potassium is nonpeptide angiotensin II (AII) receptor antagonist and is orally active. It belongs to a new class of drugs introduced for clinical trials to treat hypertension.

Application

Losartan potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Losartan Potassium and Hydrochlorothiazide Tablets
Losartan Potassium Tablets

Biochem/physiol Actions

口服、强效、选择性的竞争血管紧张素II受体1型 (AT1)拮抗剂。

氯沙坦钾是一种口服、强效、选择性的竞争血管紧张素II受体1型 (AT1)拮抗剂。氯沙坦钾用于治疗高血压。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c