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Merck
CN

1370600

USP

洛伐他汀

United States Pharmacopeia (USP) Reference Standard

别名:

洛伐他汀

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关于此项目

经验公式(希尔记法):
C24H36O5
化学文摘社编号:
分子量:
404.54
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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产品名称

洛伐他汀, United States Pharmacopeia (USP) Reference Standard

SMILES string

O1[C@@H](C[C@H](CC1=O)O)CC[C@@H]2[C@H]3[C@H](C[C@H](C=C3C=C[C@@H]2C)C)OC(=O)[C@H](CC)C

InChI

1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI key

PCZOHLXUXFIOCF-BXMDZJJMSA-N

grade

pharmaceutical primary standard

API family

lovastatin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药,不可用于诊断、治疗或治愈任何疾病。

Application

洛伐他汀USP参考标准品,预期用途是USP规定的指定质量测试和检测。也用于USP各论,例如:
  • 洛伐他汀片
  • 辛伐他汀
  • 辛伐他汀片

General description

本产品按照现行药典要求提供和指定。所有为支持本产品而提供的信息,包括 SDS 和任何产品信息小册子,均由药典颁发机构制定和发布。如需进一步的信息和支持,请访问现行药典网站。如需进一步信息和支持,请访问现行药典网站。

Other Notes

可能适用相应的销售限制。

pictograms

Health hazard

signalword

Warning

Hazard Classifications

Carc. 2 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Enrico Peiretti et al.
Experimental eye research, 124, 11-16 (2014-05-06)
Starting from previous studies showing that patients with cognitive deficit present neutral lipids (NLs) accumulation in cytoplasm of their peripheral blood mononuclear cells (PBMCs) and considering that there is epidemiological evidence linking age-related macular degeneration (AMD) to cognitive deficit, the
Jonathan A Tobert
Nature reviews. Drug discovery, 2(7), 517-526 (2003-06-20)
In the 1950s and 1960s, it became apparent that elevated concentrations of plasma cholesterol were a major risk factor for the development of coronary heart disease, which led to the search for drugs that could reduce plasma cholesterol. One possibility
Md Khalid Pasha et al.
Biomedical chromatography : BMC, 20(3), 282-293 (2005-09-07)
A specific, accurate, precise and reproducible high-performance liquid chromatographic (HPLC) method was developed and validated for the simultaneous quantitation of five 3-hydroxy-3-methyglutaryl coenzyme A (HMG-CoA) reductase inhibitors, viz. atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin, in pharmaceutical formulations and extended the
Giovanni Provenzano et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(40), 13281-13288 (2014-10-03)
Genome-wide association studies indicated the homeobox-containing transcription factor Engrailed-2 (En2) as a candidate gene for autism spectrum disorders (ASD). Accordingly, En2 knock-out (En2(-/-)) mice show anatomical and behavioral "ASD-like" features, including decreased sociability and learning deficits. The molecular pathways underlying
Dae-Hyoung Yoo et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(9), 1508-1513 (2014-06-21)
Orally administered drugs may be metabolized by intestinal microbial enzymes before absorption into the blood. Accordingly, coadministration of drugs affecting the metabolic activities of gut microbes (e.g., antibiotics) may lead to drug-drug interactions (DDI). In this study, gut microbiota-mediated DDI

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