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经验公式（希尔记法）:
C24H38O5
化学文摘社编号:
分子量:
406.56
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
产品名称
Lovastatin Related Compound A, United States Pharmacopeia (USP) Reference Standard
SMILES string
O1[C@@H](C[C@H](CC1=O)O)CC[C@@H]2[C@H]3[C@H](C[C@@H](C[C@@H]3OC(=O)[C@H](CC)C)C)C=C[C@@H]2C
InChI
1S/C24H38O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,14-21,23,25H,5,8-13H2,1-4H3/t14-,15-,16-,17-,18+,19+,20-,21-,23+/m0/s1
InChI key
IFIFFBWHLKGTMO-LDIGTXGYSA-N
grade
pharmaceutical primary standard
API family
lovastatin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.
C H Heathcock et al.
Journal of medicinal chemistry, 30(10), 1858-1873 (1987-10-01)
The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase: (1) functional and stereoisomeric analogues that possess the full carbon skeleton
G Albers-Schönberg et al.
The Journal of antibiotics, 34(5), 507-512 (1981-05-01)
A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahydro-naphthalene system are described. Comparative data for dihydromevinolin and mevinolin in three biological assays are
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