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文件

安全信息

1380105

USP

褪黑素

United States Pharmacopeia (USP) Reference Standard

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别名:
N-乙酰基-5-甲氧基色胺
经验公式（希尔记法）:
C13H16N2O2
CAS号:
73-31-4
分子量:
232.28
Beilstein:
205542
MDL编号:
MFCD00005655
PubChem化学物质编号:
329750346
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

melatonin

制造商/商品名称

USP

mp

116.5-118 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

COc1ccc2[nH]cc(CCNC(C)=O)c2c1

InChI

1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

InChI key

DRLFMBDRBRZALE-UHFFFAOYSA-N

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Melatonin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay, performance tests, strength, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Melatonin Tablets
  • Melatonin

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Melatonin
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 5143-5143 (2020)
Melatonin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(6), 5144-5144 (2013)
Ismail Gögenur et al.
Journal of pineal research, 57(1), 10-15 (2014-04-09)
The aim was to examine the effect of perioperative melatonin treatment on clinical cardiac morbidity and markers of myocardial ischemia in patients undergoing elective surgery for abdominal aortic aneurism. Reperfusion injury results in increased cardiac morbidity in patients undergoing surgery
Reuben K Wong et al.
Digestive diseases and sciences, 60(1), 186-194 (2014-08-06)
Probiotics have treatment efficacy in irritable bowel syndrome (IBS), but the exact mechanism remains obscure. One hypothesis is the mediation of melatonin levels, leading to changes in IBS symptoms. The purpose of this study was to evaluate the effects of
P Boyce et al.
Acta psychiatrica Scandinavica. Supplementum, (444)(444), 16-23 (2013-08-09)
Disturbances in circadian rhythms have been associated with major depression and may be an underlying mechanism for the disorder. Resynchronisation of circadian rhythms may provide a new approach to treatment, especially by manipulating melatonin secretion. Melatonin is secreted at night
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