Merck
CN
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文件

1426002

USP

甲基多巴 倍半水合物

United States Pharmacopeia (USP) Reference Standard

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别名:
3-(3,4-二羟基苯基)-2-甲基-L-丙氨酸, L-甲基多巴, MK-351
经验公式（希尔记法）:
C10H13NO4 · 1.5H2O
CAS号:
41372-08-1
分子量:
238.24
Beilstein:
2417244
MDL编号:
MFCD00004186
PubChem化学物质编号:
329750434
NACRES:
NA.24

等级

pharmaceutical primary standard

API family

methyldopa

manufacturer/tradename

USP

mp

≥300 °C

application(s)

pharmaceutical (small molecule)

格式

neat

SMILES string

C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1

InChI key

CJCSPKMFHVPWAR-JTQLQIEISA-N

Gene Information

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

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相关类别

应用

Methyldopa USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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P A van Zwieten et al.
Hypertension (Dallas, Tex. : 1979), 6(5 Pt 2), II28-II33 (1984-09-01)
Clonidine (Catapres, Catapresan), guanfacine (Estulic), and methyldopa (Aldomet) are the prototypes of centrally acting antihypertensive drugs. Clonidine and guanfacine are lipophilic drugs that readily penetrate into the brain, where they stimulate alpha-adrenergic receptors in the pontomedullary region. The stimulation of
Qi Chang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 805(2), 275-280 (2004-05-12)
A new method for the determination of tranexamic acid (TA) in human plasma using high performance liquid chromatography with tandem mass spectrometric detection was described. TA and the internal standard, methyldopa, was extracted from a 200 l plasma sample by
Li-Ting Liao et al.
Clinica chimica acta; international journal of clinical chemistry, 436, 72-77 (2014-05-13)
Uric acid measurement has become increasingly important, and electrochemically modified detection method based portable devices hold a dominant position in the market for point of care and self-monitoring of uric acid blood levels. However, there has been a lack of

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